Gene Information
Gene NameTRIM23
OrganismHomo sapiens (Human)
Gene Length574
Protein NamesE3 ubiquitin-protein ligase TRIM23 (EC 2.3.2.27) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (RING-type E3 ubiquitin transferase TRIM23) (Tripartite motif-containing protein 23)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000113595 )
Evolutionary StageEumetazoa
AlphaFoldDBP36406
Gene CardTRIM23
Uniprot IDP36406
PfamPF00025; PF00643; PF13445
In ASDno
Allosteric Predictionno (-0.600896282)
Ortholog in AnimalsAlpaca_ TRIM23 ( ortholog_one2one )
Dog_ TRIM23 ( ortholog_one2one )
GuineaPig_ TRIM23 ( ortholog_one2one )
Macaque_ TRIM23 ( ortholog_one2one )
Mouse_ Trim23 ( ortholog_one2one )
Pig_ TRIM23 ( ortholog_one2one )
Rat_ Trim23 ( ortholog_one2one )
Rabbit_ TRIM23 ( ortholog_one2one )
OhnologsNA
ParalogsARL5C, ARF4, ARL10, ARL16, ARL2, ARFRP1, ARL17B, ARL17A, ARF3, ARF1, ARL1, ARL8B, ARL4D, ARL9, ARL14, ARL4A, ARL6, ARL13B, ARL13A, ARL15, ARL11, ARL5A, ARF5, ARL3, ARL8A, SAR1B, ARF6, ARL4C, ARL5B, SAR1A
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001445(Rat);0.017391(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5VZV  (X-ray  1.81A  5VZW  (X-ray  2.28A 
DBSNP rs34046496 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:28871090}. Endomembrane system {ECO:0000269|PubMed:9671726}. Golgi apparatus membrane {ECO:0000269|PubMed:9671726}. Lysosome membrane {ECO:0000269|PubMed:9671726}. Note=Membrane-associated with the Golgi complex and lysosomal structures.
Mouse PG classificationNA
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