Gene Information
Gene NameTRIM17
OrganismHomo sapiens (Human)
Gene Length477
Protein NamesE3 ubiquitin-protein ligase TRIM17 (EC 2.3.2.27) (RING finger protein 16) (RING-type E3 ubiquitin transferase TRIM17) (Testis RING finger protein) (Tripartite motif-containing protein 17)
Target NameNA
Target TypeNA
Gene Age382 ( ENSG00000162931 )
3 ( ENSG00000285344 )
Evolutionary StageMammalia
AlphaFoldDBQ9Y577
Gene CardTRIM17
Uniprot IDQ9Y577
PfamPF00622; PF00643; PF13445
In ASDno
Allosteric Predictionno (-0.591315351)
Ortholog in AnimalsAlpaca_ TRIM17 ( ortholog_one2one )
GuineaPig_ TRIM17 ( ortholog_one2one )
Macaque_ TRIM17 ( ortholog_one2one )
Mouse_ Trim17 ( ortholog_one2one )
Pig_ TRIM17 ( ortholog_one2one )
Rat_ Trim17 ( ortholog_one2one )
Rabbit_ TRIM17 ( ortholog_one2one )
OhnologsTRIM69
ParalogsTRIM42, TRIM13, TRIM31, TRIM49B, TRIM49C, TRIM49, TRIM33, TRIM69, TRIM71, TRIM77, TRIM28, TRIM3, TRIM46, TRIM58, TRIM38, TRIM5, TRIM37, MID1, TRIM7, TRIM36, TRIM44, TRIML2, TRIM2, TRIM63, TRIM73, TRIM74, TRIM65, TRIML1, MID2, TRIM32, TRIM14, TRIM34, TRIM54, TRIM55, TRIM52, TRIM41, TRIM11, PML, TRIM43, TRIM43B, TRIM21, TRIM6, TRIM27, TRIM40, TRIM51G, TRIM51, TRIM9, TRIM67, TRIM25, TRIM49D1, TRIM48, TRIM49D2, TRIM68, TRIM24, TRIM64C, TRIM64, TRIM64B, TRIM60, TRIM61, TRIM4, TRIM10, BSPRY, TRIM56, TRIM29, TRIM8, MEFV, TRIM15, TRIM22, TRIM35, TRIM16, TRIM47, TRIM45, TRIM72, TRIM62, TRIM50, TRIM75, TRIM66, RNF39, TRIM26, TRIM39
Tissuetestis, cerebellar.hemisphere, cerebellum, nucleus.accumbens
Tissue SpecificityAlmost exclusively in the testis. {ECO:0000269|PubMed:19358823}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:27562068}. Lysosome {ECO:0000269|PubMed:27562068}.
Mouse PG classificationNA
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