| Gene Information | |
|---|---|
| Gene Name | AATK |
| Organism | Homo sapiens (Human) |
| Gene Length | 1374 |
| Protein Names | Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000181409 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6ZMQ8 |
| Gene Card | AATK |
| Uniprot ID | Q6ZMQ8 |
| Pfam | PF07714 |
| In ASD | no |
| Allosteric Prediction | no (-0.111920083) |
| Ortholog in Animals | Alpaca_ AATK ( ortholog_one2one ) Dog_ AATK ( ortholog_one2one ) GuineaPig_ AATK ( ortholog_one2one ) Macaque_ AATK ( ortholog_one2one ) Mouse_ Aatk ( ortholog_one2one ) Pig_ AATK ( ortholog_one2one ) Rat_ Aatk ( ortholog_one2one ) |
| Ohnologs | LMTK3, LMTK2 |
| Paralogs | LMTK3 |
| Tissue | cerebral.cortex, duodenum, small.intestine, brain |
| Tissue Specificity | Expressed in brain. {ECO:0000269|PubMed:10837911}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1337040042 rs8082016 rs7503604 rs56032966 rs56313973 rs55793641 rs55856613 rs36000545 rs55713566 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:10837911}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:10837911}. Note=Predominantly perinuclear. |
| Mouse PG classification | NA |
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