| Gene Information | |
|---|---|
| Gene Name | TRH |
| Organism | Homo sapiens (Human) |
| Gene Length | 242 |
| Protein Names | Pro-thyrotropin-releasing hormone (Pro-TRH) (Prothyroliberin) [Cleaved into: Thyrotropin-releasing hormone (TRH) (Protirelin) (TSH-releasing factor) (Thyroliberin) (Thyrotropin-releasing factor) (TRF)] |
| Target Name | thyrotropin-releasing hormone |
| Target Type | Clinical trial target |
| Gene Age | 950 ( ENSG00000170893 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P20396 |
| Gene Card | TRH |
| Uniprot ID | P20396 |
| Pfam | PF05438 |
| In ASD | no |
| Allosteric Prediction | yes (0.740175005) |
| Ortholog in Animals | Alpaca_ TRH ( ortholog_one2one ) Dog_ TRH ( ortholog_one2one ) Macaque_ TRH ( ortholog_one2one ) Mouse_ Trh ( ortholog_one2one ) Pig_ TRH ( ortholog_one2one ) Rat_ Trh ( ortholog_one2one ) Rabbit_ TRH ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | endometrium |
| Tissue Specificity | Hypothalamus. Expressed in the hair follicle epithelium (at protein level). {ECO:0000269|PubMed:19825978}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs5658 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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