| Gene Information | |
|---|---|
| Gene Name | TRBF2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 542 |
| Protein Names | Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q15554 |
| Gene Card | TERF2 |
| Uniprot ID | Q15554 |
| Pfam | PF00249; PF16772; PF08558 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.323046(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1H6P (X-ray 2.20A ) 1VF9 (NMR - ) 1VFC (NMR - ) 1W0U (X-ray 1.80A ) 1XG1 (NMR - ) 3BU8 (X-ray 2.15A ) 3BUA (X-ray 2.50A ) 3K6G (X-ray 1.95A ) 3SJM (X-ray 1.35A ) 4M7C (X-ray 2.05A ) 4RQI (X-ray 2.44A ) 5WQD (X-ray 3.00A ) 5XYF (X-ray 2.20A ) 6J67 (X-ray 2.05A ) 7C5D (X-ray 2.15A ) |
| DBSNP | rs35874485 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:20655466}. Chromosome, telomere {ECO:0000269|PubMed:20655466}. Note=Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase. |
| Mouse PG classification | NA |
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