| Gene Information | |
|---|---|
| Gene Name | TRASK |
| Organism | Homo sapiens (Human) |
| Gene Length | 836 |
| Protein Names | CUB domain-containing protein 1 (Membrane glycoprotein gp140) (Subtractive immunization M plus HEp3-associated 135 kDa protein) (SIMA135) (Transmembrane and associated with src kinases) (CD antigen CD318) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H5V8 |
| Gene Card | CDCP1 |
| Uniprot ID | Q9H5V8 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells. {ECO:0000269|PubMed:11466621, ECO:0000269|PubMed:12660814, ECO:0000269|PubMed:15153610, ECO:0000269|PubMed:16007225}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3749191 rs35428731 rs9874077 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Shedding may also lead to a soluble peptide.; [Isoform 3]: Secreted. |
| Mouse PG classification | NA |
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