Gene Information
Gene NameSORCS1
OrganismHomo sapiens (Human)
Gene Length1168
Protein NamesVPS10 domain-containing receptor SorCS1 (hSorCS)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000108018 )
Evolutionary StageEukaryota
AlphaFoldDBQ8WY21
Gene CardSORCS1
Uniprot IDQ8WY21
PfamPF00801; PF15902; PF15901
In ASDno
Allosteric Predictionno (-1.40576771)
Ortholog in AnimalsAlpaca_ SORCS1 ( ortholog_one2one )
Dog_ SORCS1 ( ortholog_one2one )
GuineaPig_ SORCS1 ( ortholog_one2one )
Macaque_ SORCS1 ( ortholog_one2one )
Mouse_ Sorcs1 ( ortholog_one2one )
Pig_ SORCS1 ( ortholog_one2one )
Rat_ Sorcs1 ( ortholog_one2one )
Rabbit_ SORCS1 ( ortholog_one2one )
OhnologsSORCS2
ParalogsSORCS3, SORCS2, SORL1, SORT1
Tissuethyroid, tibial.nerve
Tissue SpecificityDetected in fetal and infant brain and in fetal retina.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane;
Single-pass type I membrane protein.
Mouse PG classificationNA
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