| Gene Information | |
|---|---|
| Gene Name | TRAPPC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 140 |
| Protein Names | Trafficking protein particle complex subunit 2 (Sedlin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000196459 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P0DI81 |
| Gene Card | TRAPPC2 |
| Uniprot ID | P0DI81 |
| Pfam | PF04628 |
| In ASD | no |
| Allosteric Prediction | no (-0.73144581) |
| Ortholog in Animals | Alpaca_ TRAPPC2 ( ortholog_one2one ) Dog_ TRAPPC2 ( ortholog_one2many ) Macaque_ TRAPPC2 ( ortholog_one2one ) Mouse_ Trappc2 ( ortholog_one2many ) Pig_ TRAPPC2 ( ortholog_one2many ) Rat_ Trappc2 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | TRAPPC2B, TRAPPC2L |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, placenta and lymphocytes. {ECO:0000269|PubMed:10431248}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);0.065826(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs769218264 rs104894948 |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:11031107}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000269|PubMed:11031107}. Nucleus {ECO:0000269|PubMed:20498720, ECO:0000269|PubMed:25918224}. Cytoplasm {ECO:0000269|PubMed:20498720}. Note=Localized in perinuclear granular structures. {ECO:0000269|PubMed:11031107}. |
| Mouse PG classification | NA |
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