| Gene Information | |
|---|---|
| Gene Name | NMNAT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 252 |
| Protein Names | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 (NMN/NaMN adenylyltransferase 3) (Nicotinamide-nucleotide adenylyltransferase 3) (NMN adenylyltransferase 3) (Nicotinate-nucleotide adenylyltransferase 3) (NaMN adenylyltransferase 3) (EC 2.7.7.18) (Pyridine nucleotide adenylyltransferase 3) (PNAT-3) (EC 2.7.7.1) |
| Target Name | nicotinamide mononucleotide adenylyltransferase 3 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163864 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96T66 |
| Gene Card | NMNAT3 |
| Uniprot ID | Q96T66 |
| Pfam | PF01467 |
| In ASD | no |
| Allosteric Prediction | no (-0.450423256) |
| Ortholog in Animals | Alpaca_ NMNAT3 ( ortholog_one2one ) Dog_ NMNAT3 ( ortholog_one2one ) GuineaPig_ NMNAT3 ( ortholog_one2one ) Macaque_ RBP1 ( ortholog_one2one ) Mouse_ Nmnat3 ( ortholog_one2one ) Pig_ NMNAT3 ( ortholog_one2one ) Rat_ Nmnat3 ( ortholog_one2one ) |
| Ohnologs | NMNAT1 |
| Paralogs | NMNAT1, NMNAT2 |
| Tissue | NA |
| Tissue Specificity | Expressed in lung and spleen with lower levels in placenta and kidney. {ECO:0000269|PubMed:12574164, ECO:0000269|PubMed:16118205}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1NUP (X-ray 1.90A ) 1NUQ (X-ray 1.90A ) 1NUR (X-ray 2.15A ) 1NUS (X-ray 2.20A ) 1NUT (X-ray 1.90A ) 1NUU (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:12574164, ECO:0000269|PubMed:16118205}. |
| Mouse PG classification | NA |
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