Gene Information
Gene NameCENPX
OrganismHomo sapiens (Human)
Gene Length81
Protein NamesCentromere protein X (CENP-X) (FANCM-associated histone fold protein 2) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Retinoic acid-inducible gene D9 protein homolog) (Stimulated by retinoic acid gene 13 protein homolog)
Target NameNA
Target TypeNA
Gene Age424 ( ENSG00000169689 )
Evolutionary StageMammalia
AlphaFoldDBA8MT69
Gene CardCENPX
Uniprot IDA8MT69
PfamPF09415
In ASDno
Allosteric Predictionno (-1.767412275)
Ortholog in AnimalsDog_ CENPX ( ortholog_one2one )
GuineaPig_ CENPX ( ortholog_one2one )
Macaque_ CENPX ( ortholog_one2one )
Rabbit_ CENPX ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.082877(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4DRA  (X-ray  2.41A  )  4DRB  (X-ray  2.63A  )  4E44  (X-ray  2.10A  )  4E45  (X-ray  2.00A  )  4NDY  (X-ray  7.00A  )  4NE1  (X-ray  6.50A  )  4NE3  (X-ray  1.80A  )  4NE5  (X-ray  2.50A  )  4NE6  (X-ray  2.10A  )  7R5S  (EM  2.83A  )  7YWX  (EM  12.00A  ) 
DBSNP NA 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}. Chromosome, centromere {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}. Note=Assembly of CENPS and CENPX and its partner subunits CENPT and CENPW at centromeres occurs through a dynamic exchange mechanism. Although exchange is continuous in the cell cycle, de novo assembly starts principally during mid-late S phase and is complete by G2. CENPX being less stably bound at the kinetochore than CENPS. {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}.
Mouse PG classificationNA
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