| Gene Information | |
|---|---|
| Gene Name | TRAF7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 670 |
| Protein Names | E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000131653 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6Q0C0 |
| Gene Card | TRAF7 |
| Uniprot ID | Q6Q0C0 |
| Pfam | PF00400; PF13445 |
| In ASD | no |
| Allosteric Prediction | no (-0.443305859) |
| Ortholog in Animals | Alpaca_ TRAF7 ( ortholog_one2one ) Dog_ TRAF7 ( ortholog_one2one ) GuineaPig_ TRAF7 ( ortholog_one2one ) Macaque_ TRAF7 ( ortholog_one2one ) Mouse_ Traf7 ( ortholog_one2one ) Pig_ TRAF7 ( ortholog_one2one ) Rat_ Traf7 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FBXW12, FBXW11, WDR49, FBXO36, BTRC, FBXW8, PAAF1, WDR64, EFCAB8, WDR86, FBXO16, FBXW9, FBXW7, WDR54 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed with high levels in skeletal muscle, heart, colon, spleen, kidney, liver and placenta. {ECO:0000269|PubMed:15001576}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1567252467 rs1567252659 rs1567254067 rs1331463984 |
| Subcellular location [CC] | Cytoplasmic vesicle {ECO:0000269|PubMed:14743216}. Note=Colocalizes with MAP3K3 to vesicle-like structures throughout the cytoplasm. |
| Mouse PG classification | NA |
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