| Gene Information | |
|---|---|
| Gene Name | GPR119 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | Glucose-dependent insulinotropic receptor (G-protein coupled receptor 119) |
| Target Name | glucose-dependent insulinotropic receptor |
| Target Type | Successful target |
| Gene Age | 454 ( ENSG00000147262 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TDV5 |
| Gene Card | GPR119 |
| Uniprot ID | Q8TDV5 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999933231) |
| Ortholog in Animals | Alpaca_ GPR119 ( ortholog_one2one ) Dog_ GPR119 ( ortholog_one2one ) GuineaPig_ GPR119 ( ortholog_one2one ) Macaque_ GPR119 ( ortholog_one2one ) Mouse_ Gpr119 ( ortholog_one2one ) Pig_ GPR119 ( ortholog_one2one ) Rat_ Gpr119 ( ortholog_one2one ) Rabbit_ GPR119 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | S1PR1, S1PR5, S1PR2, S1PR3, S1PR4, LPAR1, LPAR2, LPAR3, MC5R, MC1R, MC2R, MC3R, MC4R, GPR3, GPR6, GPR12, CNR1, CNR2 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in the pancreas, especially in the islets. {ECO:0000269|PubMed:15607732}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7XZ5 (EM 3.10A ) 7XZ6 (EM 2.80A ) |
| DBSNP | rs5975187 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |