| Gene Information | |
|---|---|
| Gene Name | THEMIS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 643 |
| Protein Names | Protein THEMIS2 (Induced by contact to basement membrane 1 protein) (Protein ICB-1) (Thymocyte-expressed molecule involved in selection protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000130775 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5TEJ8 |
| Gene Card | THEMIS2 |
| Uniprot ID | Q5TEJ8 |
| Pfam | PF12736 |
| In ASD | no |
| Allosteric Prediction | no (-1.315924932) |
| Ortholog in Animals | Alpaca_ THEMIS2 ( ortholog_one2one ) Dog_ THEMIS2 ( ortholog_one2one ) GuineaPig_ THEMIS2 ( ortholog_one2one ) Macaque_ THEMIS2 ( ortholog_one2one ) Mouse_ Themis2 ( ortholog_one2one ) Pig_ THEMIS2 ( ortholog_one2one ) Rat_ Themis2 ( ortholog_one2one ) Rabbit_ THEMIS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | THEMIS |
| Tissue | NA |
| Tissue Specificity | Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1. {ECO:0000269|PubMed:9563507}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35995543 rs3766400 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q91YX0}. Cytoplasm {ECO:0000250|UniProtKB:Q91YX0}. |
| Mouse PG classification | NA |
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