| Gene Information | |
|---|---|
| Gene Name | TPRKB |
| Organism | Homo sapiens (Human) |
| Gene Length | 175 |
| Protein Names | EKC/KEOPS complex subunit TPRKB (PRPK-binding protein) (TP53RK-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000144034 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y3C4 |
| Gene Card | TPRKB |
| Uniprot ID | Q9Y3C4 |
| Pfam | PF08617 |
| In ASD | no |
| Allosteric Prediction | no (-1.214272773) |
| Ortholog in Animals | Alpaca_ TPRKB ( ortholog_one2one ) Dog_ TPRKB ( ortholog_one2one ) GuineaPig_ TPRKB ( ortholog_one2one ) Macaque_ TPRKB ( ortholog_one2one ) Mouse_ Tprkb ( ortholog_one2one ) Pig_ TPRKB ( ortholog_one2one ) Rat_ Tprkb ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12659830}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001578(Rat);0.023529(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3ENP (X-ray 2.48A ) 6WQX (X-ray 2.53A ) |
| DBSNP | rs1553433412 rs1233885358 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:12659830, ECO:0000269|PubMed:28805828}. Nucleus {ECO:0000269|PubMed:12659830, ECO:0000269|PubMed:22912744, ECO:0000269|PubMed:28805828}. |
| Mouse PG classification | NA |
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