| Gene Information | |
|---|---|
| Gene Name | TPPP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 170 |
| Protein Names | Tubulin polymerization-promoting protein family member 2 (Protein p25-beta) (TPPP/p18) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000179636 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P59282 |
| Gene Card | TPPP2 |
| Uniprot ID | P59282 |
| Pfam | PF05517 |
| In ASD | no |
| Allosteric Prediction | no (-1.564499256) |
| Ortholog in Animals | Alpaca_ TPPP2 ( ortholog_one2one ) Dog_ TPPP2 ( ortholog_one2one ) GuineaPig_ TPPP2 ( ortholog_one2one ) Macaque_ TPPP2 ( ortholog_one2one ) Mouse_ Tppp2 ( ortholog_one2one ) Pig_ TPPP2 ( ortholog_one2one ) Rat_ Tppp2 ( ortholog_one2one ) Rabbit_ TPPP2 ( ortholog_one2one ) |
| Ohnologs | TPPP3, TPPP |
| Paralogs | TPPP3, TPPP |
| Tissue | testis |
| Tissue Specificity | Expressed in spermatids (PubMed:23436708). Detected in liver cancer (at protein level) (PubMed:23436708). {ECO:0000269|PubMed:23436708}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9624 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000305|PubMed:17105200}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q0P5Y3}. Note=Present in the middle piece of sperm tail. {ECO:0000250|UniProtKB:Q0P5Y3}. |
| Mouse PG classification | NA |
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