| Gene Information | |
|---|---|
| Gene Name | RCVRN |
| Organism | Homo sapiens (Human) |
| Gene Length | 200 |
| Protein Names | Recoverin (Cancer-associated retinopathy protein) (Protein CAR) |
| Target Name | recoverin |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000109047 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P35243 |
| Gene Card | RCVRN |
| Uniprot ID | P35243 |
| Pfam | PF13499; PF13833 |
| In ASD | no |
| Allosteric Prediction | no (-0.048877633) |
| Ortholog in Animals | Alpaca_ RCVRN ( ortholog_one2one ) Dog_ RCVRN ( ortholog_one2one ) GuineaPig_ RCVRN ( ortholog_one2one ) Mouse_ Rcvrn ( ortholog_one2one ) Pig_ RCVRN ( ortholog_one2one ) Rat_ Rcvrn ( ortholog_one2one ) Rabbit_ RCVRN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KCNIP4, KCNIP2, GUCA1B, VSNL1, KCNIP1, HPCAL1, NCS1, KCNIP3, GUCA1C, GUCA1A, CLXN, NCALD, HPCAL4, HPCA |
| Tissue | NA |
| Tissue Specificity | Retina and pineal gland. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002528(Rat);0.030769(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2D8N (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Photoreceptor inner segment {ECO:0000250|UniProtKB:P34057}. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:P34057}. Photoreceptor outer segment membrane {ECO:0000250|UniProtKB:P21457}; Lipid-anchor {ECO:0000250|UniProtKB:P21457}; Cytoplasmic side {ECO:0000250|UniProtKB:P21457}. Perikaryon {ECO:0000250|UniProtKB:P34057}. Note=Primarily expressed in the inner segments of light-adapted rod photoreceptors, approximately 10% of which translocates from photoreceptor outer segments upon light stimulation (By similarity). Targeting of myristoylated protein to rod photoreceptor outer segments is calcium dependent (By similarity). {ECO:0000250|UniProtKB:P21457, ECO:0000250|UniProtKB:P34057}. |
| Mouse PG classification | NA |
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