Gene Information
Gene NameP2RY5
OrganismHomo sapiens (Human)
Gene Length344
Protein NamesLysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBP43657
Gene CardLPAR6
Uniprot IDP43657
PfamPF00001
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityExpressed ubiquitously, including in skin and hair follicle cells. Detected in both Henle's and Huxley's layers of the inner root sheath of the hair follicle and in suprabasal layers of the epidermis (at protein level). Expressed at low levels in peripheral blood leukocytes. {ECO:0000269|PubMed:11004484, ECO:0000269|PubMed:18297070, ECO:0000269|PubMed:18297072}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1060585  rs879255262  rs4151553  rs121434307  rs121434309  rs17071686 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:18297070};
Multi-pass membrane protein {ECO:0000269|PubMed:18297070}.
Mouse PG classificationNA
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