| Gene Information | |
|---|---|
| Gene Name | TPM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 285 |
| Protein Names | Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5) |
| Target Name | tropomyosin alpha-3 chain |
| Target Type | NA |
| Gene Age | 8 ( ENSG00000143549 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P06753 |
| Gene Card | TPM3 |
| Uniprot ID | P06753 |
| Pfam | PF00261 |
| In ASD | no |
| Allosteric Prediction | no (-0.182110985) |
| Ortholog in Animals | Alpaca_ TPM3 ( ortholog_one2one ) Dog_ TPM3 ( ortholog_one2one ) GuineaPig_ TPM3 ( ortholog_one2one ) Macaque_ TPM3 ( ortholog_one2one ) Rat_ Tpm3 ( ortholog_one2one ) |
| Ohnologs | TPM1, TPM4, TPM2 |
| Paralogs | TPM1, TPM2, TPM4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6OTN (X-ray 2.40A ) |
| DBSNP | rs199474711 rs80358247 rs1571418855 rs199474713 rs121964853 rs121964853 rs121964854 rs121964854 rs121964852 rs199474715 rs199474716 rs199474717 rs199474718 rs797046047 rs1553248515 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000305}. |
| Mouse PG classification | NA |
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