| Gene Information | |
|---|---|
| Gene Name | TPK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 243 |
| Protein Names | Thiamin pyrophosphokinase 1 (hTPK1) (EC 2.7.6.2) (Placental protein 20) (PP20) (Thiamine pyrophosphokinase 1) |
| Target Name | thiamin pyrophosphokinase 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000196511 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9H3S4 |
| Gene Card | TPK1 |
| Uniprot ID | Q9H3S4 |
| Pfam | PF04265; PF04263 |
| In ASD | no |
| Allosteric Prediction | no (-0.653338366) |
| Ortholog in Animals | Alpaca_ TPK1 ( ortholog_one2one ) Dog_ TPK1 ( ortholog_one2one ) GuineaPig_ TPK1 ( ortholog_one2one ) Macaque_ TPK1 ( ortholog_one2one ) Mouse_ Tpk1 ( ortholog_one2one ) Pig_ TPK1 ( ortholog_one2one ) Rat_ Tpk1 ( ortholog_one2one ) Rabbit_ TPK1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues. {ECO:0000269|PubMed:11342111, ECO:0000269|PubMed:11342117}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3S4Y (X-ray 1.80A ) |
| DBSNP | rs387906936 rs387906935 rs371271054 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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