Gene Information
Gene NameTPIP
OrganismHomo sapiens (Human)
Gene Length522
Protein NamesPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (EC 3.1.3.67) (Lipid phosphatase TPIP) (TPTE and PTEN homologous inositol lipid phosphatase)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ6XPS3
Gene CardTPTE2
Uniprot IDQ6XPS3
PfamPF10409
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityIsoform 3 is expressed in testis, brain and stomach while isoform 4 seems to be testis-specific. {ECO:0000269|PubMed:11716755}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2497218  rs2497218 
Subcellular location [CC][Isoform 3]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:11716755};
Multi-pass membrane protein {ECO:0000255}.;
[Isoform 1]: Endoplasmic reticulum membrane {ECO:0000269|PubMed:14659893};
Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:14659893};
Multi-pass membrane protein {ECO:0000255}.;
[Isoform 4]: Cytoplasm {ECO:0000269|PubMed:11716755}.
Mouse PG classificationNA
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