| Gene Information | |
|---|---|
| Gene Name | TPC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 816 |
| Protein Names | Two pore channel protein 1 (Two pore calcium channel protein 1) (Voltage-dependent calcium channel protein TPC1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9ULQ1 |
| Gene Card | TPCN1 |
| Uniprot ID | Q9ULQ1 |
| Pfam | PF00520 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highest expression found in the heart and kidney, and lowest expression found in the spleen. {ECO:0000269|PubMed:10574461}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Lysosome membrane {ECO:0000269|PubMed:19620632, ECO:0000269|PubMed:23063126, ECO:0000269|PubMed:25722412}; Multi-pass membrane protein {ECO:0000269|PubMed:19620632}. Endosome membrane {ECO:0000269|PubMed:19620632, ECO:0000269|PubMed:20880839, ECO:0000269|PubMed:23063126, ECO:0000269|PubMed:25722412}; Multi-pass membrane protein {ECO:0000269|PubMed:19620632}. Early endosome membrane {ECO:0000250|UniProtKB:Q9EQJ0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9EQJ0}. Recycling endosome membrane {ECO:0000250|UniProtKB:Q9EQJ0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9EQJ0}. |
| Mouse PG classification | NA |
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