| Gene Information | |
|---|---|
| Gene Name | TOX3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 576 |
| Protein Names | TOX high mobility group box family member 3 (CAG trinucleotide repeat-containing gene F9 protein) (Trinucleotide repeat-containing gene 9 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000103460 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O15405 |
| Gene Card | TOX3 |
| Uniprot ID | O15405 |
| Pfam | PF00505 |
| In ASD | no |
| Allosteric Prediction | no (-0.684219122) |
| Ortholog in Animals | Alpaca_ TOX3 ( ortholog_one2one ) Dog_ TOX3 ( ortholog_one2one ) Macaque_ TOX3 ( ortholog_one2one ) Mouse_ Tox3 ( ortholog_one2one ) Pig_ TOX3 ( ortholog_one2one ) Rat_ Tox3 ( ortholog_one2one ) Rabbit_ TOX3 ( ortholog_one2one ) |
| Ohnologs | TOX2, TOX4, TOX |
| Paralogs | SP140, HMGB2, UBTF, TOX4, UBTFL1, HMGB1P1, HMGB1, SP100, SMARCE1, HMGB3, HMG20A, TFAM, HMG20B, SSRP1, TOX2, TOX, SP110, HMGB4, SP140L, HMGXB4 |
| Tissue | brain, kidney, small.intestine |
| Tissue Specificity | Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe. {ECO:0000269|PubMed:21172805}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16951186 rs13332816 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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