| Gene Information | |
|---|---|
| Gene Name | TNNI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 210 |
| Protein Names | Troponin I, cardiac muscle (Cardiac troponin I) |
| Target Name | troponin i, cardiac muscle |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000129991 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P19429 |
| Gene Card | TNNI3 |
| Uniprot ID | P19429 |
| Pfam | PF00992; PF11636 |
| In ASD | yes |
| Allosteric Prediction | yes (0.231721313) |
| Ortholog in Animals | Alpaca_ TNNI3 ( ortholog_one2one ) GuineaPig_ TNNI3 ( ortholog_one2one ) Mouse_ Tnni3 ( ortholog_one2one ) Pig_ TNNI3 ( ortholog_one2one ) Rat_ Tnni3 ( ortholog_one2one ) |
| Ohnologs | TNNI2 |
| Paralogs | TNNI2, TNNI1 |
| Tissue | heart, left.atrium, left.ventricle, mitral.valve, pulmonary.valve |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001899(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1J1D (X-ray 2.61A ) 1J1E (X-ray 3.30A ) 1LXF (NMR - ) 1MXL (NMR - ) 1OZS (NMR - ) 2KGB (NMR - ) 2KRD (NMR - ) 2L1R (NMR - ) 2MZP (NMR - ) 2N7L (NMR - ) 4Y99 (X-ray 2.00A ) 5VLN (NMR - ) 5W88 (NMR - ) 5WCL (NMR - ) 6KN7 (EM 6.60A ) 6KN8 (EM 4.80A ) 6MV3 (NMR - ) 7JGI (NMR - ) 7SC2 (X-ray 1.81A ) 7SC3 (X-ray 2.23A ) 7SUP (NMR - ) 7SVC (NMR - ) 7SWG (NMR - ) 7SWI (NMR - ) 7SXC (NMR - ) 7SXD (NMR - ) 7UH9 (NMR - ) 7UHA (NMR - ) |
| DBSNP | rs397516359 rs267607130 rs3729712 rs77615401 rs777177571 rs397516347 rs121917760 rs104894724 rs104894724 rs397516353 rs397516354 rs397516354 rs727504242 rs121917761 rs104894730 rs267607129 rs397516357 rs104894729 rs104894727 rs727504275 rs104894725 |
| Subcellular location [CC] | NA |
| Mouse PG classification | HPG |
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