| Gene Information | |
|---|---|
| Gene Name | TNXB |
| Organism | Homo sapiens (Human) |
| Gene Length | 4244 |
| Protein Names | Tenascin-X (TN-X) (Hexabrachion-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000168477 ) 3 ( ENSG00000206258 ) 3 ( ENSG00000229341 ) 3 ( ENSG00000229353 ) 3 ( ENSG00000231608 ) 3 ( ENSG00000233323 ) 3 ( ENSG00000236221 ) 3 ( ENSG00000236236 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | TNXB |
| Uniprot ID | P22105 |
| Pfam | PF07974; PF18720; PF00147; PF00041 |
| In ASD | no |
| Allosteric Prediction | no (-0.664163496) |
| Ortholog in Animals | GuineaPig_ TNXB ( ortholog_one2one ) Macaque_ TNXB ( ortholog_one2one ) Mouse_ Tnxb ( ortholog_one2one ) Pig_ TNXB ( ortholog_one2one ) Rat_ AABR07044388.2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TNC, FCN1, ANGPTL5, FGL1, FCN2, ANGPTL4, FIBCD1, TNN, ANGPTL6, FGB, ANGPT4, ANGPTL1, MFAP4, TNR, ANGPTL3, FGA, ANGPTL2, ANGPTL7, FCN3, FNDC7, FGL2, FGG, ANGPT1, FN1, ANGPT2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB-short is only expressed in the adrenal gland. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CUH (NMR - ) 2CUI (NMR - ) 2CUM (NMR - ) |
| DBSNP | rs368512272 rs1150752 rs204896 rs17201609 rs17201602 rs204900 rs121912575 rs185819 rs17207923 rs2269428 rs2269428 rs12524664 rs2269429 rs1009382 rs1473257039 rs7742632 rs587777682 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix. |
| Mouse PG classification | NA |
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