| Gene Information | |
|---|---|
| Gene Name | VASH2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 355 |
| Protein Names | Tubulinyl-Tyr carboxypeptidase 2 (EC 3.4.17.17) (Vasohibin-2) (Vasohibin-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143494 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86V25 |
| Gene Card | VASH2 |
| Uniprot ID | Q86V25 |
| Pfam | PF14822 |
| In ASD | no |
| Allosteric Prediction | no (-0.727636631) |
| Ortholog in Animals | Alpaca_ VASH2 ( ortholog_one2one ) Dog_ VASH2 ( ortholog_one2one ) GuineaPig_ VASH2 ( ortholog_one2one ) Macaque_ VASH2 ( ortholog_one2one ) Mouse_ Vash2 ( ortholog_one2one ) Pig_ VASH2 ( ortholog_one2one ) Rat_ Vash2 ( ortholog_one2one ) Rabbit_ VASH2 ( ortholog_one2one ) |
| Ohnologs | VASH1 |
| Paralogs | VASH1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6J4O (X-ray 2.30A ) 6J4P (X-ray 1.60A ) 6J4Q (X-ray 2.70A ) 6J4S (X-ray 2.80A ) 6J4V (X-ray 2.10A ) 6QBY (X-ray 2.09A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:19204325}. Secreted {ECO:0000269|PubMed:20736312}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:31235911}. Note=Mainly localizes in the cytoplasm (PubMed:19204325). Some fraction is secreted via a non-canonical secretion system; interaction with SVBP promotes secretion (PubMed:20736312). Associates with microtubules (PubMed:31235911). {ECO:0000269|PubMed:19204325, ECO:0000269|PubMed:20736312, ECO:0000269|PubMed:31235911}. |
| Mouse PG classification | NA |
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