| Gene Information | |
|---|---|
| Gene Name | TNP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 138 |
| Protein Names | Nuclear transition protein 2 (TP-2) (TP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000178279 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q05952 |
| Gene Card | TNP2 |
| Uniprot ID | Q05952 |
| Pfam | PF01254 |
| In ASD | no |
| Allosteric Prediction | no (-1.147367335) |
| Ortholog in Animals | Alpaca_ TNP2 ( ortholog_one2one ) Dog_ TNP2 ( ortholog_one2one ) Macaque_ TNP2 ( ortholog_one2one ) Mouse_ Tnp2 ( ortholog_one2one ) Pig_ TNP2 ( ortholog_one2one ) Rat_ Tnp2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | Expressed by spermatids (at protein level). {ECO:0000269|PubMed:9809674}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11640138 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:P11101}. Nucleus, nucleolus {ECO:0000250|UniProtKB:P11101}. Chromosome {ECO:0000250|UniProtKB:P11101}. Note=Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is mediated by IPO4. Nucleolar localization requires the protein to be phosphorylated (By similarity). {ECO:0000250|UniProtKB:P11101, ECO:0000250|UniProtKB:P11378}. |
| Mouse PG classification | NA |
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