| Gene Information | |
|---|---|
| Gene Name | ACSS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 689 |
| Protein Names | Acetyl-coenzyme A synthetase 2-like, mitochondrial (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1) (Propionate--CoA ligase) (EC 6.2.1.17) |
| Target Name | acetyl-coenzyme a synthetase 2-like, mitochondrial |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000154930 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9NUB1 |
| Gene Card | ACSS1 |
| Uniprot ID | Q9NUB1 |
| Pfam | PF16177; PF00501; PF13193 |
| In ASD | no |
| Allosteric Prediction | no (-0.541311157) |
| Ortholog in Animals | Alpaca_ ACSS1 ( ortholog_one2one ) Dog_ ACSS1 ( ortholog_one2one ) GuineaPig_ ACSS1 ( ortholog_one2one ) Macaque_ ACSS1 ( ortholog_one2one ) Mouse_ Acss1 ( ortholog_one2one ) Pig_ ACSS1 ( ortholog_one2one ) Rat_ Acss1 ( ortholog_one2one ) Rabbit_ ACSS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACSM4, ACSS2, ACSM2B, ACSM2A, AACS, ACSM3, AASDH, ACSS3, ACSM1, ACSM5, ACSM6, ACSF2, ACSF3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3GLR (X-ray 1.80A ) 3GLT (X-ray 2.10A ) 3GLU (X-ray 2.50A ) 4BVE (X-ray 2.05A ) 4BVF (X-ray 2.70A ) 4BVG (X-ray 2.50A ) 4C78 (X-ray 2.00A ) 5Y4H (X-ray 2.60A ) 5YTK (X-ray 2.70A ) |
| DBSNP | rs6050249 |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:16788062}. |
| Mouse PG classification | NA |
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