| Gene Information | |
|---|---|
| Gene Name | TNIP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 325 |
| Protein Names | TNFAIP3-interacting protein 3 (A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000050730 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96KP6 |
| Gene Card | TNIP3 |
| Uniprot ID | Q96KP6 |
| Pfam | PF16516 |
| In ASD | no |
| Allosteric Prediction | no (-0.860756662) |
| Ortholog in Animals | Alpaca_ TNIP3 ( ortholog_one2one ) Dog_ TNIP3 ( ortholog_one2one ) GuineaPig_ TNIP3 ( ortholog_one2one ) Macaque_ TNIP3 ( ortholog_one2one ) Mouse_ Tnip3 ( ortholog_one2one ) Pig_ TNIP3 ( ortholog_one2one ) Rat_ Tnip3 ( ortholog_one2one ) Rabbit_ TNIP3 ( ortholog_one2one ) |
| Ohnologs | TNIP1 |
| Paralogs | TNIP1, TNIP2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL. {ECO:0000269|PubMed:11345586, ECO:0000269|PubMed:17088249}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10000692 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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