Gene Information
Gene NameCD300C
OrganismHomo sapiens (Human)
Gene Length224
Protein NamesCMRF35-like molecule 6 (CLM-6) (CD300 antigen-like family member C) (CMRF35-A1) (CMRF-35) (Immunoglobulin superfamily member 16) (IgSF16) (CD antigen CD300c)
Target NameNA
Target TypeNA
Gene Age332 ( ENSG00000167850 )
Evolutionary StageVertebrata
AlphaFoldDBQ08708
Gene CardCD300C
Uniprot IDQ08708
PfamPF07686
In ASDno
Allosteric Predictionno (-1.179356207)
Ortholog in AnimalsAlpaca_ CD300C ( ortholog_one2one )
Macaque_ CD300C ( ortholog_one2one )
Mouse_ Cd300c ( ortholog_one2many )
Mouse_ Cd300c2 ( ortholog_one2many )
Pig_ CD300C ( ortholog_one2one )
Rat_ AABR07030773.1 ( ortholog_one2many )
Rat_ AABR07030793.1 ( ortholog_one2many )
Rat_ RGD1562667 ( ortholog_one2many )
Rat_ RGD1559482 ( ortholog_one2many )
Rat_ Cd300a ( ortholog_one2many )
OhnologsNA
ParalogsTREML1, FCAMR, CD300LD, TMIGD3, CD300H, CD300LF, CD300LG, CD300A, FCMR, PIGR, CD300E, TREM2, CD300LB
Tissuewhole.blood
Tissue SpecificityPresent on the surface of monocytes, neutrophils, a proportion of peripheral blood T- and B-lymphocytes and lymphocytic cell lines.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11870245 
Subcellular location [CC]Cell membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
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