| Gene Information | |
|---|---|
| Gene Name | NINJ1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 152 |
| Protein Names | Ninjurin-1 (Nerve injury-induced protein 1) [Cleaved into: Secreted ninjurin-1 (Soluble ninjurin-1)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000131669 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92982 |
| Gene Card | NINJ1 |
| Uniprot ID | Q92982 |
| Pfam | PF04923 |
| In ASD | no |
| Allosteric Prediction | no (-1.492036059) |
| Ortholog in Animals | Alpaca_ NINJ1 ( ortholog_one2one ) GuineaPig_ NINJ1 ( ortholog_one2one ) Macaque_ NINJ1 ( ortholog_one2one ) Mouse_ Ninj1 ( ortholog_one2one ) Pig_ NINJ1 ( ortholog_one2one ) Rat_ Ninj1 ( ortholog_one2one ) Rabbit_ NINJ1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NINJ2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in both adult and embryonic tissues, primarily those of epithelial origin. {ECO:0000269|PubMed:8780658}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2275848 |
| Subcellular location [CC] | [Ninjurin-1]: Cell membrane {ECO:0000250|UniProtKB:O70131}; Multi-pass membrane protein {ECO:0000255}. Synaptic cell membrane {ECO:0000250|UniProtKB:O70131}; Multi-pass membrane protein {ECO:0000255}.; [Secreted ninjurin-1]: Secreted {ECO:0000305|PubMed:32883094}. |
| Mouse PG classification | NA |
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