| Gene Information | |
|---|---|
| Gene Name | MMP27 |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | Matrix metalloproteinase-27 (MMP-27) (EC 3.4.24.-) |
| Target Name | matrix metalloproteinase-27 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000137675 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H306 |
| Gene Card | MMP27 |
| Uniprot ID | Q9H306 |
| Pfam | PF00045; PF00413; PF01471 |
| In ASD | no |
| Allosteric Prediction | no (-0.398270312) |
| Ortholog in Animals | Alpaca_ MMP27 ( ortholog_one2one ) Dog_ MMP27 ( ortholog_one2one ) GuineaPig_ MMP27 ( ortholog_one2one ) Macaque_ MMP27 ( ortholog_one2one ) Mouse_ Mmp27 ( ortholog_one2one ) Pig_ MMP27 ( ortholog_one2one ) Rat_ Mmp27 ( ortholog_one2one ) Rabbit_ MMP27 ( ortholog_one2one ) |
| Ohnologs | MMP25, MMP2, MMP11, MMP15 |
| Paralogs | MMP24, MMP16, MMP21, MMP14, MMP2, MMP1, MMP19, MMP23B, MMP10, MMP9, MMP12, MMP15, MMP17, MMP25, MMP28, MMP13, MMP7, MMP20, MMP26, HPX, MMP8, MMP3, MMP11 |
| Tissue | NA |
| Tissue Specificity | Expressed in B-cells (PubMed:14506071). Expressed in a subset of endometrial macrophages related to menstruation and in ovarian and peritoneal endometriotic lesions (at protein level)(PubMed:24810263). {ECO:0000269|PubMed:14506071, ECO:0000269|PubMed:24810263}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12099177 rs1939015 rs2846707 rs1276286 rs35616217 rs2509010 rs35822551 |
| Subcellular location [CC] | Endoplasmic reticulum membrane; Peripheral membrane protein {ECO:0000269|PubMed:24548619}. Note=Retained in the endoplasmic reticulum. {ECO:0000269|PubMed:24548619}. |
| Mouse PG classification | NA |
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