| Gene Information | |
|---|---|
| Gene Name | LNX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 728 |
| Protein Names | E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000072201 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TBB1 |
| Gene Card | LNX1 |
| Uniprot ID | Q8TBB1 |
| Pfam | PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.720866333) |
| Ortholog in Animals | Alpaca_ LNX1 ( ortholog_one2one ) Dog_ LNX1 ( ortholog_one2one ) GuineaPig_ LNX1 ( ortholog_one2one ) Macaque_ LNX1 ( ortholog_one2one ) Mouse_ Lnx1 ( ortholog_one2one ) Pig_ LNX1 ( ortholog_one2one ) Rat_ Lnx1 ( ortholog_one2one ) Rabbit_ LNX1 ( ortholog_one2one ) |
| Ohnologs | LNX2 |
| Paralogs | FRMPD2, LNX2, STXBP4, PATJ, MPDZ |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, placenta, kidney, pancreas and brain. {ECO:0000269|PubMed:11521506}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.008333(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 3B76 (X-ray 1.75A ) 5H7R (X-ray 1.70A ) 5H7S (X-ray 3.49A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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