| Gene Information | |
|---|---|
| Gene Name | TMPRSS15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1019 |
| Protein Names | Enteropeptidase (EC 3.4.21.9) (Enterokinase) (Serine protease 7) (Transmembrane protease serine 15) [Cleaved into: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000154646 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P98073 |
| Gene Card | TMPRSS15 |
| Uniprot ID | P98073 |
| Pfam | PF00431; PF00057; PF00629; PF01390; PF15494; PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.230197964) |
| Ortholog in Animals | Alpaca_ TMPRSS15 ( ortholog_one2one ) Dog_ TMPRSS15 ( ortholog_one2one ) GuineaPig_ TMPRSS15 ( ortholog_one2one ) Macaque_ TMPRSS15 ( ortholog_one2one ) Mouse_ Tmprss15 ( ortholog_one2one ) Pig_ TMPRSS15 ( ortholog_one2one ) Rat_ Tmprss15 ( ortholog_one2one ) Rabbit_ TMPRSS15 ( ortholog_one2one ) |
| Ohnologs | TMPRSS4, TMPRSS13, ST14 |
| Paralogs | TMPRSS6, HPN, TMPRSS11E, ST14, TMPRSS3, TMPRSS13, TMPRSS11D, TMPRSS2, PRSS22, TMPRSS11A, TMPRSS7, TMPRSS11B, TMPRSS9, TMPRSS5, PRSS21, PRSS41, TMPRSS11F |
| Tissue | duodenum, small.intestine |
| Tissue Specificity | Intestinal brush border. |
| Pharmacological Animal Models | 0.044130(Chimpanzee);NULL(Mouse);0.001000(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DGJ (X-ray 1.90A ) 6ZOV (X-ray 2.19A ) |
| DBSNP | rs35987974 rs2824804 rs2824790 rs8134187 rs2273204 rs11088674 rs2824721 rs8130110 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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