Gene Information
Gene NameTMPRSS13
OrganismHomo sapiens (Human)
Gene Length586
Protein NamesTransmembrane protease serine 13 (EC 3.4.21.-) (Membrane-type mosaic serine protease) (Mosaic serine protease)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000137747 )
Evolutionary StageVertebrata
AlphaFoldDBQ9BYE2
Gene CardTMPRSS13
Uniprot IDQ9BYE2
PfamPF15494; PF00089
In ASDno
Allosteric Predictionno (-0.633042846)
Ortholog in AnimalsAlpaca_ TMPRSS13 ( ortholog_one2one )
Dog_ TMPRSS13 ( ortholog_one2one )
GuineaPig_ TMPRSS13 ( ortholog_one2one )
Macaque_ TMPRSS13 ( ortholog_one2one )
Mouse_ Tmprss13 ( ortholog_one2one )
Pig_ TMPRSS13 ( ortholog_one2one )
Rat_ Tmprss13 ( ortholog_one2one )
OhnologsPRSS33, TPSG1, TMPRSS15, TMPRSS3, TMPRSS2
ParalogsTMPRSS15, TMPRSS6, HPN, TMPRSS11E, ST14, TMPRSS3, TMPRSS11D, TMPRSS2, PRSS22, TMPRSS11A, TMPRSS7, TMPRSS11B, TMPRSS9, TMPRSS5, PRSS21, PRSS41, TMPRSS11F
Tissueskin, cervix, heart, placenta, tongue, zone.of.skin, lower.leg.skin, suprapubic.skin
Tissue SpecificityIsoform 1 and isoform 3 are predominantly expressed in lung, placenta, pancreas, and prostate. Isoform 3 is weakly expressed in testis and peripheral blood lymphocytes. {ECO:0000269|PubMed:11267681}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type II membrane protein {ECO:0000305}.
Mouse PG classificationNA
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