| Gene Information | |
|---|---|
| Gene Name | TMPRSS11D |
| Organism | Homo sapiens (Human) |
| Gene Length | 418 |
| Protein Names | Transmembrane protease serine 11D (EC 3.4.21.-) (Airway trypsin-like protease) [Cleaved into: Transmembrane protease serine 11D non-catalytic chain; Transmembrane protease serine 11D catalytic chain] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000153802 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O60235 |
| Gene Card | TMPRSS11D |
| Uniprot ID | O60235 |
| Pfam | PF01390; PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.853298147) |
| Ortholog in Animals | Alpaca_ TMPRSS11D ( ortholog_one2one ) GuineaPig_ TMPRSS11D ( ortholog_one2one ) Macaque_ TMPRSS11D ( ortholog_one2one ) Mouse_ Tmprss11d ( ortholog_one2one ) Pig_ TMPRSS11D ( ortholog_one2one ) Rat_ Tmprss11d ( ortholog_one2one ) Rabbit_ TMPRSS11D ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TMPRSS15, TMPRSS6, HPN, TMPRSS11E, ST14, TMPRSS3, TMPRSS13, TMPRSS2, PRSS22, TMPRSS11A, TMPRSS7, TMPRSS11B, TMPRSS9, TMPRSS5, PRSS21, PRSS41, TMPRSS11F |
| Tissue | esophagus, tonsil, tongue, esophagus.mucosa, vagina |
| Tissue Specificity | Located in the cells of the submucosal serous glands of the bronchi and trachea. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Single-pass type II membrane protein. Note=Activated by cleavage and secreted.; [Transmembrane protease serine 11D catalytic chain]: Secreted. Note=Activated by cleavage and secreted. |
| Mouse PG classification | NA |
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