Gene Information
Gene NameTMPO
OrganismHomo sapiens (Human)
Gene Length454
Protein NamesLamina-associated polypeptide 2, isoforms beta/gamma (Thymopoietin, isoforms beta/gamma) (TP beta/gamma) (Thymopoietin-related peptide isoforms beta/gamma) (TPRP isoforms beta/gamma) [Cleaved into: Thymopoietin (TP) (Splenin); Thymopentin (TP5)]
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000120802 )
Evolutionary StageEumetazoa
AlphaFoldDBP42167
Gene CardTMPO
Uniprot IDP42167
PfamPF03020; PF08198
In ASDno
Allosteric Predictionno (-0.608263068)
Ortholog in AnimalsDog_ TMPO ( ortholog_one2one )
GuineaPig_ TMPO ( ortholog_one2one )
Macaque_ TMPO ( ortholog_one2one )
Mouse_ Tmpo ( ortholog_one2one )
OhnologsNA
ParalogsLEMD1
TissueNA
Tissue SpecificityExpressed in many tissues. Most abundant in adult thymus and fetal liver.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7133258  rs1058288 
Subcellular location [CC]Nucleus inner membrane;
Single-pass type II membrane protein. Note=Tightly associated with the nuclear lamina.;
[Isoform Zeta]: Cytoplasm {ECO:0000269|PubMed:18403046}.
Mouse PG classificationNA
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