| Gene Information | |
|---|---|
| Gene Name | BPIFB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 614 |
| Protein Names | BPI fold-containing family B member 4 (Ligand-binding protein RY2G5) (Long palate, lung and nasal epithelium carcinoma-associated protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000186191 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P59827 |
| Gene Card | BPIFB4 |
| Uniprot ID | P59827 |
| Pfam | PF01273; PF02886 |
| In ASD | no |
| Allosteric Prediction | no (-1.64637266) |
| Ortholog in Animals | Alpaca_ BPIFB4 ( ortholog_one2one ) Dog_ BPIFB4 ( ortholog_one2one ) GuineaPig_ BPIFB4 ( ortholog_one2one ) Macaque_ BPIFB4 ( ortholog_one2one ) Mouse_ Bpifb4 ( ortholog_one2one ) Pig_ BPIFB4 ( ortholog_one2one ) Rat_ Bpifb4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BPIFB3, BPIFB6, BPIFB2, BPIFA2, BPIFA1, BPIFA3, BPIFB1, BPI, PLTP, LBP, CETP, BPIFC |
| Tissue | NA |
| Tissue Specificity | Expressed in nasal tissue. {ECO:0000269|PubMed:11971875}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2424943 rs4339026 rs2424943 rs2070325 rs2070325 rs2889732 rs11699009 rs11696307 |
| Subcellular location [CC] | Secreted {ECO:0000250}. Cytoplasm {ECO:0000269|PubMed:12837268}. |
| Mouse PG classification | NA |
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