| Gene Information | |
|---|---|
| Gene Name | SPATA25 |
| Organism | Homo sapiens (Human) |
| Gene Length | 227 |
| Protein Names | Spermatogenesis-associated protein 25 (Testis-specific gene 23 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000149634 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9BR10 |
| Gene Card | SPATA25 |
| Uniprot ID | Q9BR10 |
| Pfam | PF15218 |
| In ASD | no |
| Allosteric Prediction | no (-1.987895275) |
| Ortholog in Animals | Alpaca_ SPATA25 ( ortholog_one2one ) Dog_ SPATA25 ( ortholog_one2one ) GuineaPig_ SPATA25 ( ortholog_one2one ) Macaque_ SPATA25 ( ortholog_one2one ) Mouse_ Spata25 ( ortholog_one2one ) Pig_ SPATA25 ( ortholog_one2one ) Rat_ Spata25 ( ortholog_one2one ) Rabbit_ SPATA25 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in testis (at protein level). Expression is lower in patients with obstructive azoospermia than in fertile controls and is not detected in patients with non-obstructive azoospermia. {ECO:0000269|PubMed:19240080}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3827040 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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