| Gene Information | |
|---|---|
| Gene Name | TMEM8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 771 |
| Protein Names | Post-GPI attachment to proteins factor 6 (EC 3.1.1.4) (GPI processing phospholipase A2) (GPI-PLA2) (Protein M83) (Transmembrane protein 6) (Transmembrane protein 8) (Transmembrane protein 8A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9HCN3 |
| Gene Card | PGAP6 |
| Uniprot ID | Q9HCN3 |
| Pfam | PF12036 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in pancreas, placenta, spleen, liver, kidney, bone marrow, peripheral blood leukocytes and tonsil. {ECO:0000269|PubMed:11006113}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11248931 rs2071915 rs3743887 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:27881714}; Multi-pass membrane protein {ECO:0000255}. Lysosome membrane {ECO:0000269|PubMed:21752829}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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