Gene Information
Gene NameST18
OrganismHomo sapiens (Human)
Gene Length1047
Protein NamesSuppression of tumorigenicity 18 protein (Zinc finger protein 387)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000147488 )
Evolutionary StageEumetazoa
AlphaFoldDBO60284
Gene CardST18
Uniprot IDO60284
PfamPF08474; PF01530
In ASDno
Allosteric Predictionno (-1.108715789)
Ortholog in AnimalsAlpaca_ ST18 ( ortholog_one2one )
Dog_ ST18 ( ortholog_one2one )
GuineaPig_ ST18 ( ortholog_one2one )
Macaque_ ST18 ( ortholog_one2one )
Mouse_ St18 ( ortholog_one2one )
Pig_ ST18 ( ortholog_one2one )
Rat_ St18 ( ortholog_one2one )
Rabbit_ ST18 ( ortholog_one2one )
OhnologsMYT1, MYT1L
ParalogsIRF2BP1, IRF2BP2, MYT1L, IRF2BPL, MYT1
Tissuebrain, cerebellar.hemisphere, cerebellum
Tissue SpecificityDetected at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Detected at even lower levels in mammary epithelial cells and breast cancer cells. {ECO:0000269|PubMed:15489893}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2CS8  (NMR 
DBSNP rs2303460 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:15489893}.
Mouse PG classificationNA
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