Gene Information
Gene NameTKFC
OrganismHomo sapiens (Human)
Gene Length575
Protein NamesTriokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)]
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000149476 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ3LXA3
Gene CardTKFC
Uniprot IDQ3LXA3
PfamPF02733; PF02734
In ASDno
Allosteric Predictionno (-0.424722002)
Ortholog in AnimalsAlpaca_ TKFC ( ortholog_one2one )
Dog_ TKFC ( ortholog_one2one )
GuineaPig_ TKFC ( ortholog_one2one )
Macaque_ TKFC ( ortholog_one2one )
Mouse_ Tkfc ( ortholog_one2one )
Pig_ TKFC ( ortholog_one2one )
Rat_ Tkfc ( ortholog_one2one )
Rabbit_ TKFC ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityDetected in erythrocytes (at protein level). {ECO:0000269|PubMed:4688871}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2260655  rs35723406  rs1590578831  rs547013163 
Subcellular location [CC]NA
Mouse PG classificationNA
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