| Gene Information | |
|---|---|
| Gene Name | SGIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 828 |
| Protein Names | SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000118473 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9BQI5 |
| Gene Card | SGIP1 |
| Uniprot ID | Q9BQI5 |
| Pfam | PF10291 |
| In ASD | no |
| Allosteric Prediction | yes (0.0530172) |
| Ortholog in Animals | Alpaca_ SGIP1 ( ortholog_one2one ) Dog_ SGIP1 ( ortholog_one2one ) GuineaPig_ SGIP1 ( ortholog_one2one ) Macaque_ SGIP1 ( ortholog_one2one ) Mouse_ Sgip1 ( ortholog_one2one ) Pig_ SGIP1 ( ortholog_one2one ) Rat_ Sgip1 ( ortholog_one2one ) Rabbit_ SGIP1 ( ortholog_one2one ) |
| Ohnologs | FCHO1, FCHO2 |
| Paralogs | PSTPIP2, FCHO2, PSTPIP1, GAS7, FCHO1 |
| Tissue | cerebral.cortex |
| Tissue Specificity | Specifically expressed in brain. {ECO:0000269|PubMed:15919751}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5AWR (X-ray 2.50A ) 5AWS (X-ray 2.00A ) 5AWT (X-ray 2.70A ) 5AWU (X-ray 2.70A ) 6A9Y (X-ray 2.70A ) |
| DBSNP | rs17490057 rs7526812 rs17855645 rs17854026 |
| Subcellular location [CC] | Membrane, clathrin-coated pit {ECO:0000305|PubMed:20946875}; Peripheral membrane protein {ECO:0000305|PubMed:20946875}; Cytoplasmic side {ECO:0000305|PubMed:20946875}. |
| Mouse PG classification | NA |
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