Gene Information
Gene NameTMEM250
OrganismHomo sapiens (Human)
Gene Length139
Protein NamesTransmembrane protein 250 (Herpes virus UL25-binding protein)
Target NameNA
Target TypeNA
Gene Age1292 ( ENSG00000238227 )
Evolutionary StageNA
AlphaFoldDBH0YL14
Gene CardTMEM250
Uniprot IDH0YL14
PfamPF17685
In ASDno
Allosteric Predictionno (-1.485243686)
Ortholog in AnimalsAlpaca_ TMEM250 ( ortholog_one2one )
Dog_ TMEM250 ( ortholog_one2one )
GuineaPig_ TMEM250 ( ortholog_one2one )
Macaque_ TMEM250 ( ortholog_one2one )
Mouse_ Tmem250-ps ( ortholog_one2one )
Pig_ TMEM250 ( ortholog_one2one )
Rat_ Tmem250 ( ortholog_one2one )
OhnologsNA
ParalogsSEPTIN11, SEPTIN8, SEPTIN12, SEPTIN10, SEPTIN1, SEPTIN9, SEPTIN3, SEPTIN7, SEPTIN6, SEPTIN5, SEPTIN2, SEPTIN14
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}. Nucleus {ECO:0000269|PubMed:21667337}. Cytoplasm {ECO:0000269|PubMed:21667337}. Note=Upon HHV-1 infection, accumulates arround the nuclear membrane and translocates into the nucleus.
Mouse PG classificationNA
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