Gene Information
Gene NameTMEM249
OrganismHomo sapiens (Human)
Gene Length235
Protein NamesCation channel sperm-associated auxiliary subunit TMEM249 (Transmembrane protein 249)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000261587 )
3 ( ENSG00000285272 )
Evolutionary StageEumetazoa
AlphaFoldDBQ2WGJ8
Gene CardTMEM249
Uniprot IDQ2WGJ8
PfamPF15158
In ASDno
Allosteric Predictionno (-1.636738624)
Ortholog in AnimalsAlpaca_ TMEM249 ( ortholog_one2many )
Dog_ TMEM249 ( ortholog_one2one )
Macaque_ TMEM249 ( ortholog_one2one )
Mouse_ Tmem249 ( ortholog_one2one )
Pig_ TMEM249 ( ortholog_one2one )
Rabbit_ TMEM249 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell projection, cilium, flagellum membrane {ECO:0000250|UniProtKB:A0A2R8VHF7};
Multi-pass membrane protein {ECO:0000250|UniProtKB:A0A2R8VHF7}. Note=Predominantly located in the principal piece of the sperm tail. {ECO:0000250|UniProtKB:A0A2R8VHF7}.
Mouse PG classificationNA
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