| Gene Information | |
|---|---|
| Gene Name | ABCB7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 752 |
| Protein Names | Iron-sulfur clusters transporter ABCB7, mitochondrial (ATP-binding cassette sub-family B member 7, mitochondrial) (ATP-binding cassette transporter 7) (ABC transporter 7 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000131269 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O75027 |
| Gene Card | ABCB7 |
| Uniprot ID | O75027 |
| Pfam | PF00664; PF00005 |
| In ASD | no |
| Allosteric Prediction | no (-0.581915639) |
| Ortholog in Animals | Alpaca_ ABCB7 ( ortholog_one2one ) Dog_ ABCB7 ( ortholog_one2one ) GuineaPig_ ABCB7 ( ortholog_one2one ) Macaque_ ABCB7 ( ortholog_one2one ) Mouse_ Abcb7 ( ortholog_one2one ) Pig_ ABCB7 ( ortholog_one2one ) Rat_ Abcb7 ( ortholog_one2one ) Rabbit_ ABCB7 ( ortholog_one2one ) |
| Ohnologs | ABCB6 |
| Paralogs | ABCB6, TAP1, ABCB11, ABCB4, ABCB9, ABCB8, TAP2, ABCB1, ABCB10, ABCB5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7VGF (EM 3.30A ) |
| DBSNP | rs515726147 rs72554634 rs80356713 rs80356714 rs1340989 rs1340989 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P40416}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P40416}. |
| Mouse PG classification | NA |
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