| Gene Information | |
|---|---|
| Gene Name | NIPA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 360 |
| Protein Names | Magnesium transporter NIPA2 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000140157 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N8Q9 |
| Gene Card | NIPA2 |
| Uniprot ID | Q8N8Q9 |
| Pfam | PF05653 |
| In ASD | no |
| Allosteric Prediction | no (-0.701267501) |
| Ortholog in Animals | Alpaca_ NIPA2 ( ortholog_one2one ) Dog_ NIPA2 ( ortholog_one2one ) Macaque_ NIPA2 ( ortholog_one2one ) Mouse_ Nipa2 ( ortholog_one2one ) Pig_ NIPA2 ( ortholog_one2one ) Rat_ Nipa2 ( ortholog_one2one ) Rabbit_ NIPA2 ( ortholog_one2one ) |
| Ohnologs | NIPAL1, NIPAL4 |
| Paralogs | NIPAL2, NIPA1, NIPAL1, NIPAL4, NIPAL3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:14508708}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Early endosome {ECO:0000250}. Note=Recruited to the cell membrane in response to low extracellular magnesium. {ECO:0000250}. |
| Mouse PG classification | NA |
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