| Gene Information | |
|---|---|
| Gene Name | TMEM16K |
| Organism | Homo sapiens (Human) |
| Gene Length | 660 |
| Protein Names | Anoctamin-10 (Transmembrane protein 16K) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NW15 |
| Gene Card | ANO10 |
| Uniprot ID | Q9NW15 |
| Pfam | PF04547 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the brain. Intermediate levels in the retina and heart and low levels in the placenta, liver, lung, duodenum, kidney, testis and spleen. In brain areas, highest expression in the frontal and occipital cortices and in the cerebellum. Lower expression in the fetal brain than in the adult brain. {ECO:0000269|PubMed:21092923}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5OC9 (X-ray 3.20A ) 6R65 (X-ray 3.50A ) 6R7X (EM 3.47A ) 6R7Y (EM 4.20A ) 6R7Z (EM 5.14A ) |
| DBSNP | rs3772165 rs387907089 rs17409162 rs17853862 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22075693, ECO:0000269|PubMed:22946059}; Multi-pass membrane protein {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22075693, ECO:0000269|PubMed:22946059}. Note=Shows predominantly an intracellular localization with a weak expression in the cell membrane. |
| Mouse PG classification | NA |
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