Gene Information
Gene NameSTX3A
OrganismHomo sapiens (Human)
Gene Length289
Protein NamesSyntaxin-3
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ13277
Gene CardSTX3
Uniprot IDQ13277
PfamPF05739; PF00804
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue Specificity[Isoform A]: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle. {ECO:0000269|PubMed:24726755, ECO:0000269|PubMed:33974130}.;
[Isoform B]: Expressed only in the retina. {ECO:0000269|PubMed:33974130}.;
[Isoform 3]: Ubiquitously expressed. {ECO:0000269|PubMed:29475951}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs12282741  rs34563654  rs34753750 
Subcellular location [CC][Isoform A]: Apical cell membrane {ECO:0000269|PubMed:24726755};
Single-pass type IV membrane protein {ECO:0000305}. Note=Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors. {ECO:0000250|UniProtKB:Q64704}.;
[Isoform 3]: Nucleus {ECO:0000269|PubMed:29475951}.
Mouse PG classificationNA
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