| Gene Information | |
|---|---|
| Gene Name | LTBP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1821 |
| Protein Names | Latent-transforming growth factor beta-binding protein 2 (LTBP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000168056 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q14767 |
| Gene Card | LTBP2 |
| Uniprot ID | Q14767 |
| Pfam | PF00008; PF07645; PF00683 |
| In ASD | no |
| Allosteric Prediction | no (-1.035746808) |
| Ortholog in Animals | Alpaca_ LTBP3 ( ortholog_one2one ) Dog_ LTBP3 ( ortholog_one2one ) GuineaPig_ LTBP3 ( ortholog_one2one ) Macaque_ LTBP3 ( ortholog_one2one ) Mouse_ Ltbp3 ( ortholog_one2one ) Pig_ LTBP3 ( ortholog_one2one ) Rat_ Ltbp3 ( ortholog_one2one ) |
| Ohnologs | LTBP4, LTBP2, LTBP1 |
| Paralogs | LTBP1, LTBP2, LTBP4 |
| Tissue | NA |
| Tissue Specificity | Expressed in the aorta (at protein level). Expressed in lung, weakly expressed in heart, placenta, liver and skeletal muscle. {ECO:0000269|PubMed:17293099, ECO:0000269|PubMed:7798248}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs934996 rs2304707 rs2196862 rs137854856 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:7798248}. |
| Mouse PG classification | HPG |
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