| Gene Information | |
|---|---|
| Gene Name | SLC4A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1232 |
| Protein Names | Anion exchange protein 3 (AE 3) (Anion exchanger 3) (CAE3/BAE3) (Cardiac/brain band 3-like protein) (Neuronal band 3-like protein) (Solute carrier family 4 member 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000114923 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P48751 |
| Gene Card | SLC4A3 |
| Uniprot ID | P48751 |
| Pfam | PF07565; PF00955 |
| In ASD | no |
| Allosteric Prediction | no (-0.999718461) |
| Ortholog in Animals | Alpaca_ SLC4A3 ( ortholog_one2one ) Dog_ SLC4A3 ( ortholog_one2one ) GuineaPig_ SLC4A3 ( ortholog_one2one ) Mouse_ Slc4a3 ( ortholog_one2one ) Pig_ SLC4A3 ( ortholog_one2one ) Rat_ Slc4a3 ( ortholog_one2one ) Rabbit_ SLC4A3 ( ortholog_one2one ) |
| Ohnologs | SLC4A1, SLC4A2 |
| Paralogs | SLC4A9, SLC4A2, SLC4A4, SLC4A10, SLC4A5, SLC4A11, SLC4A7, SLC4A1, SLC4A8 |
| Tissue | heart |
| Tissue Specificity | [Isoform BAE3]: Expressed in the heart. {ECO:0000269|PubMed:7923606}.; [Isoform CAE3]: Expressed in the heart. {ECO:0000269|PubMed:7923606}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs597306 rs36068948 rs635311 |
| Subcellular location [CC] | [Isoform CAE3]: Cell membrane {ECO:0000305|PubMed:7923606}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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